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fungus metabolite

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Endogenous Metabolite (9) Antibiotic (4) Apoptosis (2) Arenavirus (1) Bacterial (3) Caspase (1) Fungal (11) Glucosidase (1) Isocitrate Dehydrogenase (IDH) (1) PPAR (1) Reactive Oxygen Species (1) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (5) Infection (18) Metabolic Disease (1)

Inhibitors & Agonists

Natural
Products

Targets Recommended: Drug Metabolite Endogenous Metabolite

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N8552

Banksialactone A

Endogenous Metabolite Infection

Banksialactone A is the metabolite of an Australian fungus, Aspergillus banksianus .
HY-N10299

Guignardone J

Endogenous Metabolite Infection

Guignardone J is the secondary metabolite isolated from endophytic fungus Phyllosticta capitalensis .

Banksialactone A	Endogenous Metabolite	Infection
Banksialactone A is the metabolite of an Australian fungus, Aspergillus banksianus .

Guignardone J	Endogenous Metabolite	Infection
Guignardone J is the secondary metabolite isolated from endophytic fungus Phyllosticta capitalensis .

HY-113622

Cladospirone bisepoxide Palmarumycin C13; Diepoxin ζ; Antibiotic Sch53514	Fungal Antibiotic	Infection
Cladospirone bisepoxide is a metabolite that isolated from cultures of a fungus. Cladospirone bisepoxide displays selective antibiotic activity against several bacteria and fungi and inhibits germinations of Lepidium sativum at low concentrations .

HY-N8846

dl-Aloesol	Fungal	Infection
dl-Aloesol is a natural product that can be isolated from fungus Aspergillus sp. Aspergillus sp metabolites has cytotoxic, antibacterial, free radical scavenging, anti-parasitic, antiviral and antiproliferative activities, etc .

HY-119663

Averantin	Fungal	Infection
Averantin is the minor metabolite of the fungus Cercospora arachidicola . Averantin is an aflatoxin B1 precursor that can be used in the biosynthetic pathway .

HY-N10235

Tajixanthone

Endogenous Metabolite Others

Tajixanthone is the fungus metabolite from Aspergillus variecolor .
HY-119328

Pestalotin

Endogenous Metabolite Others

Pestalotin, a fungal lactone, is a secondary metabolite of endophytic fungus Pestalotiopsis microspore .
HY-129515

Trichodecenin II

Fungal Others

Trichodecenin II is a fungal metabolite that can be found in conidia of the fungus, Trichoderma viride .
HY-125706

1233B

Fungal Antibiotic Infection

1233B is a secondary metabolite from filamentous fungus, Fusarium sp. RK97-94 .
HY-N12194

Cytochalasin O

Others Infection

Cytochalasin O (compound 13) is a secondary metabolite of the phytopathogenic fungus P. sp. CIB-109 .

Tajixanthone	Endogenous Metabolite	Others
Tajixanthone is the fungus metabolite from Aspergillus variecolor .

Pestalotin	Endogenous Metabolite	Others
Pestalotin, a fungal lactone, is a secondary metabolite of endophytic fungus Pestalotiopsis microspore .

Trichodecenin II	Fungal	Others
Trichodecenin II is a fungal metabolite that can be found in conidia of the fungus, Trichoderma viride .

1233B	Fungal Antibiotic	Infection
1233B is a secondary metabolite from filamentous fungus, Fusarium sp. RK97-94 .

Cytochalasin O	Others	Infection
Cytochalasin O (compound 13) is a secondary metabolite of the phytopathogenic fungus P. sp. CIB-109 .

HY-N7023

7-Prenyloxycoumarin 7-O-Prenylumbelliferone	Fungal	Infection
7-Prenyloxycoumarin (7-O-Prenylumbelliferone) is a secondary metabolite from the endophytic fungus of Annulohypoxylon ilanense .

HY-N10301

Guignardone L	Toll-like Receptor (TLR)	Infection
Guignardone L is a metabolite isolated from the endophytic fungus Guignardia mangiferae with toll-like receptor 3 regulating activity .

HY-N10262

Piliformic acid	Endogenous Metabolite	Others
Piliformic acid is a fungal metabolite found in the endophytic fungus Xylariasp sp.(No. 2508) from mangrove trees from the coast of the South China Sea .

HY-N10289

Cytosporone C	Fungal	Infection
Cytosporone C is an antifungal metabolite from the Melia azedarach-Associated Fungus Diaporthe eucalyptorum. Cytosporone C exhibits antifungal activities against Alternaria solani .

HY-119821

Terphenyllin	Glucosidase	Infection
Terphenyllin is a naturally abundant p-terphenyl metabolite isolated from the coral derived fungus Aspergillus candidus, has signiﬁcant α-glucosidase inhibitory activity .

HY-N12179

Brevianamide M	Bacterial	Others
Brevianamide M (compound 4) is a metabolite of Aspergillus versicolor. This is an endophytic fungus isolated from the marine brown alga Sargassum. Brevianamide M has antimicrobial activity against Escherichia coli and Staphylococcus aureus .

HY-N7569

Demethoxyfumitremorgin C	Apoptosis Caspase PPAR	Cancer
Demethoxyfumitremorgin C is a secondary metabolite of the marine fungus, Aspergillus fumigatus. Demethoxyfumitremorgin C induces prostate cancer cell apoptosis. Demethoxyfumitremorgin C activates caspase-3, -8, and -9, leading to PARP/ cleavage .

HY-N8511

Acremine I	Fungal	Infection
Acremine I is a fungi inhibitor and also a metabolite of the endophytic fungus Acremonium byssoides. Acremine I can effectively inhibit Plasmopara viticola. Acremine I can be used for research on plant diseases, such as grape downy mildew .

HY-75564

Cyclo(Ala-Gly)	Endogenous Metabolite	Cancer
Cyclo(Ala-Gly), a metabolite of a mangrove endophytic fungus, Penicillium thomi, exhibits cytotoxicity against A549, HepG2 and HT29 cells. The IC₅₀ values range from 9.5 to 18.1 μM .

HY-N8406

Monomethylsulochrin	Bacterial Antibiotic	Infection
Monomethylsulochrin is a potent antibacterial metabolite from endophytic fungus Aspergillus fumigatus, isolated from Albizia lucidior leaves (fabaceae). Monomethylsulochrin exhibits anti-Staphylococcus aureus activity with minimum inhibitory concentration (MIC) of 31.25 μg/mL .

HY-N10184

Paecilaminol FKI-0550	Others	Infection
Paecilaminol (FKI-0550) is potent NADH-fumarate reductase inhibitor. Paecilaminol exhibits an IC₅₀ value of 5.1 μM against Ascaris suum NADH-fumarate reductase .

HY-N10288

Eucalyptacid A	Fungal Endogenous Metabolite	Infection
Eucalyptacid A, an antifungal metabolite, exhibits antifungal activities against Alternaria solani, with MIC values from 6.25 to 50 μM .

HY-142088

Beauverolide Ka	Endogenous Metabolite	Metabolic Disease
Beauverolide Ka, a cyclotetradepsipeptide, is a metabolite of Beauveria bassiana fungus. Beauverolide Ka stimulates glucose uptake in cultured rat L6 myoblasts at 50 μM. Beauverolide Ka exhibits protecting effects on HEI-OC1 cells at 10 μM and shows dose-dependent activity in both L6 myoblasts and myotubes .

HY-N10269

Phomalactone	Fungal Endogenous Metabolite	Infection
Phomalactone, produced by the fungus Nigrospora sphaerica, specifically inhibits the mycelial growth of Phytophthora infestans, with an MIC value of 2.5 mg/L . Phomalactone is phytotoxic to Z. elegans and other plant species by inhibition of seedling growth and by causing electrolyte leakage from photosynthetic tissues of both Z. elegans leaves and cucumber cotyledons .

HY-N7307

Pachybasin	Bacterial	Infection
Pachybasin is a major metabolite from culture broth of endophytic coelomyceteous AFKR-18 fungus. Pachybasin showes antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively .

HY-N12390

Alternaphenol B2	Isocitrate Dehydrogenase (IDH)	Cancer
Alternaphenol B2 is a selective IDH1 inhibitor from the coral-derived fungus Parengyodontium album SCSIO SX7W11. Alternaphenol B2 shows inhibitory activity against isocitrate dehydrogenase mutant R132H (IDH1m), with IC₅₀ values of 41.9 μM .

HY-N10113

Verrucarin J Muconomycin B	Apoptosis Arenavirus Fungal Antibiotic Reactive Oxygen Species	Infection Cancer
Verrucarin J (Muconomycin B) is a metabolite of the Myrothecium fungus family. Verrucarin J generates reactive oxygen species (ROS) and induces apoptosis of cancer cell lines, such as A549, HCT 116 and SW-620 cells. Verrucarin J shows activities against Candida albicans and Mucor miehei. Verrucarin J inhibits arenavirus Junin (JUNV) yield with an IC₅₀ of 1.2 ng/mL .

HY-N12198

Mollicellin H	Others	Cancer
Mollicellin H is a secondary metabolite of the fungus C. brasiliense and has a wide range of biological activities, including immunomodulation, cytotoxicity and anti-tumor effects. The growth inhibitory effects (GI₅₀s) of Mollicellin H on human breast cancer (Bre04), human lung (Lu04) and human neuroma (N04) cell lines are 5.1 μg/mL, 6.5 μg/mL and 2.5 μg/mL respectively .

HY-N12165

1,3,5,6-Tetrahydroxy-8-methylxanthone	Others	Others
1,3,5,6-Tetrahydroxy-8-methylxanthone (compound 8) is a dimeric 1,4-benzoquinone derivative isolated from the marine-derived fungus Penicillium genus .

Banksialactone A	Infection Structural Classification Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Disease Research Fields	Endogenous Metabolite
Banksialactone A is the metabolite of an Australian fungus, Aspergillus banksianus .

Guignardone J	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Endogenous Metabolite
Guignardone J is the secondary metabolite isolated from endophytic fungus Phyllosticta capitalensis .

Cladospirone bisepoxide Palmarumycin C13; Diepoxin ζ; Antibiotic Sch53514	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Fungal Antibiotic
Cladospirone bisepoxide is a metabolite that isolated from cultures of a fungus. Cladospirone bisepoxide displays selective antibiotic activity against several bacteria and fungi and inhibits germinations of Lepidium sativum at low concentrations .

dl-Aloesol	Structural Classification Flavonoids Microorganisms Source classification Other Flavonoids	Fungal
dl-Aloesol is a natural product that can be isolated from fungus Aspergillus sp. Aspergillus sp metabolites has cytotoxic, antibacterial, free radical scavenging, anti-parasitic, antiviral and antiproliferative activities, etc .

Averantin	Infection Quinones Microorganisms Classification of Application Fields Anthraquinones Source classification Disease Research Fields	Fungal
Averantin is the minor metabolite of the fungus Cercospora arachidicola . Averantin is an aflatoxin B1 precursor that can be used in the biosynthetic pathway .

Tajixanthone	Structural Classification Microorganisms Xanthones Classification of Application Fields Source classification Other Diseases Phenols Disease Research Fields	Endogenous Metabolite
Tajixanthone is the fungus metabolite from Aspergillus variecolor .

Pestalotin	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
Pestalotin, a fungal lactone, is a secondary metabolite of endophytic fungus Pestalotiopsis microspore .

Trichodecenin II	Alkaloids Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields	Fungal
Trichodecenin II is a fungal metabolite that can be found in conidia of the fungus, Trichoderma viride .

1233B	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Fungal Antibiotic
1233B is a secondary metabolite from filamentous fungus, Fusarium sp. RK97-94 .

Cytochalasin O	Structural Classification Natural Products Microorganisms Source classification	Others
Cytochalasin O (compound 13) is a secondary metabolite of the phytopathogenic fungus P. sp. CIB-109 .

7-Prenyloxycoumarin 7-O-Prenylumbelliferone	Infection Classification of Application Fields Isodon excisoides (Sun ex C. H. Hu) H. Hara Source classification Coumarins Phenylpropanoids Plants Umbelliferae Disease Research Fields	Fungal
7-Prenyloxycoumarin (7-O-Prenylumbelliferone) is a secondary metabolite from the endophytic fungus of Annulohypoxylon ilanense .

Guignardone L	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Toll-like Receptor (TLR)
Guignardone L is a metabolite isolated from the endophytic fungus Guignardia mangiferae with toll-like receptor 3 regulating activity .

Piliformic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
Piliformic acid is a fungal metabolite found in the endophytic fungus Xylariasp sp.(No. 2508) from mangrove trees from the coast of the South China Sea .

Cytosporone C	Infection Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	Fungal
Cytosporone C is an antifungal metabolite from the Melia azedarach-Associated Fungus Diaporthe eucalyptorum. Cytosporone C exhibits antifungal activities against Alternaria solani .

Terphenyllin	Infection Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	Glucosidase
Terphenyllin is a naturally abundant p-terphenyl metabolite isolated from the coral derived fungus Aspergillus candidus, has signiﬁcant α-glucosidase inhibitory activity .

Brevianamide M	Structural Classification Alkaloids Human Gut Microbiota Metabolites Microorganisms Other Alkaloids Source classification Endogenous metabolite	Bacterial
Brevianamide M (compound 4) is a metabolite of Aspergillus versicolor. This is an endophytic fungus isolated from the marine brown alga Sargassum. Brevianamide M has antimicrobial activity against Escherichia coli and Staphylococcus aureus .

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fungus metabolite

Inhibitors & Agonists

NaturalProducts

Natural
Products